ABSTRACT
Drivers such as COVID-19, the rising geriatric population, the increased prevalence of chronic diseases, and a focus on personalized care facilitate the recent expansion of remote medicine. The response to this manifests through the growth of telehealth. However, the inability to conduct conclusive physical tests makes monitoring, diagnosing, and treating patients restricted. Wearable devices can remotely provide valuable data on patient temperature, pulmonary condition, cardiovascular condition, and blood pressure in their current technological capabilities. However, concerns for secure patient health data, interoperability between devices, and inconsistencies in the quality of information continue to limit their widespread acceptance in healthcare. This scoping review will assess the impact of wearable devices in enhancing the capabilities of remote health and safety monitoring.
ABSTRACT
SARS-CoV-2 stands for severe acute respiratory syndrome coronavirus 2. Matrix metalloproteinases-9 (MMP-9) performs a crucial physiological role. In addition to its roleICLEin the molecular basis of lung fibrosis, this enzyme may also play a part in the "cytokine storm," which may represent one of the potential scenarios during coronavirus infection. Tissue inhibitors of metalloproteinase (TIMPs) are well-known for their ability to regulate MMP activity during remodeling of the extracellular matrix. As cytokines, they are also thought of as signaling molecules that impact on a wide range of biological processes. This study aimed to investigate the link between each of MMP-9 and TIMP-1, and COVID19 disease. A total of 58 COVID-19 patients and 30 apparently healthy adults enrolled in this study. The ORF1ab, E and N genes of SARS-CoV-2 were detected using multiplex real-time PCR, while the ELISA technique was used to estimate the level of serum MMP-9, TIMP-1, and C-reactive protein (CRP). The study results demonstrated higher concentrations of MMP-9 in COVID-19 patients (2810 ± 1160 pg/ml) compared to controls (2110 ± 850 pg/ml), with non-significant differences (p=0.002). Unlike, TIMP-1, showed considerably higher levels in the patient's group (541.53 ± 201.42 pg/ml) than in controls (276.33 ± 67.26 pg/ml) with high significant differences (p ≤ 0.001). Considering this study, TIMP-1 in COVID patients most likely play an important role in inflammatory response. Its clinical utility as a biomarker may be insufficient, but it provides a useful data in the diagnosis of COVID‐19. © 2023, Bangladesh Society for Microbiology, Immunology and Advanced Biotechnology. All rights reserved.
ABSTRACT
Drivers such as COVID-19, the rising geriatric population, the increased prevalence of chronic diseases, and a focus on personalized care facilitate the recent expansion of remote medicine. The response to this manifests through the growth of telehealth. However, the inability to conduct conclusive physical tests makes monitoring, diagnosing, and treating patients restricted. Wearable devices can remotely provide valuable data on patient temperature, pulmonary condition, cardiovascular condition, and blood pressure in their current technological capabilities. However, concerns for secure patient health data, interoperability between devices, and inconsistencies in the quality of information continue to limit their widespread acceptance in healthcare. This scoping review will assess the impact of wearable devices in enhancing the capabilities of remote health and safety monitoring.
ABSTRACT
A total of (90) blood samples were collected from male patients infected with Toxoplasmosis who recovered from COVID- 19 and attended Kamal Alsamiraai Hospital from 15 January to 15 September 2021. We measured anti-Toxoplasma antibodies (IgG and IgM) detected by ELISA, whereas Anti-COVID-19 antibodies (IgG and IgM) were estimated using Elisa and Afilias. The semen characteristics were also studied among fertile, healthy individuals (control group) and sub-fertile patients. Results showed that the mean sperm count was high among the control group (40.5±1.3x 106/ml) compared with that of the sub-fertile patients (10.3±1.75 and 8.8±1.9 x 106/ml for oligozoospermia, and oligoasthenozoospermia respectively), and it was the highest (44.7±1.4 x 106/ml) among asthenozoospermia patients. Compared to the control group, there were highly significant differences between anti-Toxoplasma IgG antibodies and anti-COVID-19 IgG antibodies (P<0.001). The mean level of Toxoplasma IgM was (11.74±8.90) and for control was (0.05±0.10), while the mean level of COVID-19 IgM was (1.91±1.06) and for control was (0.04±0.03) in sub-fertile patients. The mutation occurred in IL-IB gene A to G transgene at site 4514 of the IL-IB gene (sample code, 6383) and in the case of an invalid sample code, 2409 and 5097. In the alanine codon, the GCA codon has mutated into GCG. Also, G to A transgene occurred at site 4514 of the IL-IB gene. (sample code, 6750) In the case of an invalid sample code, it happened in 010081 and 009593. In the alanine codon, the ATG codon has mutated into ATA. © 2022 by the authors.
ABSTRACT
The study aimed at the Covid-19 infection causes increase of D- dimer level and decrease the level of the lymphocyte cell count in the early diagnosis of COVID-19 infection. In the present study that was carried out in Amariah city from 1st of July to 1st of October 2020, a total of 100 people (60 infected group with COVID-19 and 40 control group without Covid-19) who were admitted to AL-Amariah Hospital whose ages were between 15-75 years. Patients were investigated for the detection of COVID-19 by using Real-Time PCR. The current study showed that the infection with COVID-19 is affected by the age factor of the patient. The highest rate of a patient with COVID-19 was within the age groups 41- 49 and >50 years with a highly significant relation between COVID-19 and age. The results showed highly significant increase of D dimer level in infected group comparison with control group and significant decrease of lymphocyte count in infected group compression with control group.
ABSTRACT
The present world is passing a great pandemic where Bangladesh facing an unavoidable challenge to cope up with COVID-19. The government and other health organizations haveannounced somehealth warnings to prevent COVID-19 and make people aware. The study aims to explore the health warnings status (knowledge and practicesof health warnings) among low socio-economic people in Bangladesh. This cross-sectional study was conducted with 400 participants (low socio-economic people) by using the purposive sampling and semi-structured questionnaire survey over six months. This study illustrates that 60% of respondents noticed they and their family members are very aware and knowledgeable about COVID-19where 36.5% are conscious to make their family aware about corona virus. About 32% of respondents use mask when they go to outside during corona period where 25% use hand sanitizer. It is found that there is a significant association between occupation, age and perception on people’s awareness about COVID-19 at 1% level of significance where (p<0.002), (p<0.001) respectively. Along with, educational qualification is also significantly associated at 10% level of significance where (p<0.08).Most of the respondents have moderate level of knowledge and awareness about COVID-19 health warnings.